Small fiber neuropathy (SFN) is a chronic pain condition affecting small-diameter sensory and autonomic fibers, commonly linked to diabetes mellitus. Clinical features include burning pain, paresthesias, and dysautonomia. It may overlap with erythromelalgia, a rare disorder causing episodic erythema, hyperthermia, and vasomotor instability. Conventional pharmacologic therapies frequently provide inadequate relief. Spinal cord stimulation (SCS) is emerging as a promising treatment for refractory neuropathic conditions, although evidence for its efficacy in SFN and erythromelalgia remains limited.
