ePosters
Sickle cell disease is a lifelong condition marked by intense and often unpredictable episodes of pain. SCD comprises a set of inherited hemoglobinopathies resulting in characteristic sickling of RBCs, owing to the term “vaso-occlusive crisis”. Pain results when sickled RBCs cause microvascular obstruction, ischemia and tissue damage within various organ systems.1 Over time, acute pain crises lead to chronicity as a result of nociceptive pain from VOC, neuropathic pain from central sensitization and chronic inflammation.
Melanie Russell-Gillette, MD
Pain Medicine Fellow
University of Cincinnati Medical Center, Ohio, United States
Naa Dromo Korley, n/a
Medical Student
University of Cincinnati Medical Center, United States
Laura DeVita, MD
Pain Medicine Fellowship Assistant Program Director
University of Cincinnati Medical Center, United States