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Beyond Averages: Informing Clinical Decision Making in the Pharmacologic Treatment of CRPS-1 using Bayesian Network Meta-Analysis

Friday, November 14, 2025
10:01 AM - 10:09 AM CT
Location: Griffin Hall
Introduction: Complex Regional Pain Syndrome Type-1 (CRPS-1) is a rare, chronic condition with no FDA-approved treatments and no clear pharmacologic standard of care.1 While randomized controlled trials (RCTs) report average treatment effects, these have not led to clinical consensus. This study used a Bayesian network meta-analysis of 17 RCTs to move beyond average effects and estimate the probability that each treatment achieves a clinically meaningful reduction in pain on the 100mm Visual Analog Scale (VAS).