SNRI-Induced SIADH in Patient Utilizing Duloxetine for Chronic Musculoskeletal Pain

Friday, November 14, 2025

3:38 PM - 3:46 PM CT

Location: Griffin Hall - Screen 07

Introduction:

Antidepressant induced hyponatremia is a rare side effect that has been noted in the literature¹. According to Picker et al, SNRIs have a similar incidence of hyponatremia to SSRIs. When combined with patient risk factors, such as chronic pain, use of SNRIs should be monitored by clinicians as a potential cause of hyponatremia.

Submitting Author(s)

AT

Austin Thompson, MD

Resident Physician
The Ohio State University Wexner Medical Center, Ohio, United States

Co-Author(s)

JL

Jimmy Le, Medical Student

Medical Student
The Ohio State University College of Medicine, Ohio, United States
JV

Jayesh Vallabh, MD, MBA

Attending Physician
The Ohio State University Wexner Medical Center, Ohio, United States