60-Day PNS Provides Relief from Occipital Head Pain in the Presence of Migraine: A Prospective, Single-Arm Multicenter Pilot Study

Friday, November 14, 2025

8:08 AM - 8:16 AM CT

Location: 301 - 302

Introduction:

Refractory pain due to cervicogenic headache (CGH) or occipital neuralgia (ON) can produce substantial disability,¹ and the negative effects are compounded in the presence of migraine.² A recent study found 60-day peripheral nerve stimulation (PNS) produced significant relief of CGH and ON, but it excluded patients with concurrent migraine diagnoses.³ The present study collected data on the efficacy and safety of the 60-day PNS treatment among patients with ON or CGH along with concurrent migraine.

Presenting Author(s)

Narayan Kissoon, MD

Chair, Division of Headache, Department of Neurology
Mayo Clinic, United States

Co-Author(s)

MP

Matthew Pingree, MD

Professor
Mayo Clinic
Rochester, Minnesota, United States
ZM

Zachary L. McCormick, MD

Vice Chair and Associate Professor in the Department of Physical Medicine and Rehabilitation (PM&R)
University of Utah Health, United States
GG

Genaro Gutierrez, MD

Medical Director
Ambulatory Surgical Center of Austin, United States
CG

Christopher A. Gilmore, MD

President
Carolinas Pain Institute, United States
ME

Mitchell P. Engle, MD, PhD

Pain Medicine Specialist
Institute of Precision Pain Medicine, United States

Submitting Author(s)

WH

William J. Huffman, PhD

Research Engineer
SPR
Cleveland, Ohio, United States

Co-Author(s)

NC

Nathan Crosby, PhD

Senior Manager, Research and Development
SPR, United States
JB

Joshua Boggs, PhD

Chief Scientific Officer
SPR, United States