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ePosters

Moderated ePoster

Resident-Led Implementation of Continuous Non-Opioid IV Analgesia to Reduce Chronic Post-Surgical Pain

Friday, November 14, 2025
4:47 PM - 4:55 PM CT
Location: 301 - 302
Introduction:

Continuous intravenous infusions of non-opioid analgesics can augment postoperative patient recovery [1, 2, 3]. Perioperative multimodal analgesic regimens help reduce adverse events, such as chronic post-surgical pain (CPSP) [4]. Dexmedetomidine stimulates α2 receptors and exerts both supraspinal and spinal mechanisms of analgesia [1]. Lidocaine affects NMDA, muscarinic M1/M3, 5-HT3 receptors, voltage-gated calcium channels, and may possess anti-inflammatory properties [2]. Ketamine inhibits NMDA receptors, but may also affect μ-opioid, muscarinic, and γ-aminobutyric acid receptors [3].